Investigating Neuron Degeneration in Huntington’s Disease Using RNA-Seq Based Transcriptome Study

Investigating Neuron Degeneration in Huntington’s Disease Using RNA-Seq Based Transcriptome Study

Huntington’s disease (HD) is a progressive neurodegenerative disorder caused due to a CAG repeat expansion in the huntingtin (<i>HTT</i>) gene. The primary symptoms of HD include motor dysfunction such as chorea, dystonia, and involuntary movements. The primary motor cortex (BA4) is the...

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Bibliographic Details
Main Authors: Nela Pragathi Sneha, S. Akila Parvathy Dharshini, Y.-h. Taguchi, M. Michael Gromiha
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Genes
Subjects:
Huntington’s disease
Brodmann area 4
tissue-specific network analysis
variant effect
function interaction network
Online Access:https://www.mdpi.com/2073-4425/14/9/1801

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https://www.mdpi.com/2073-4425/14/9/1801

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