Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Abstract Background Binge ethanol exposure during adolescence reduces hippocampal neurogenesis, a reduction which persists throughout adulthood despite abstinence. This loss of neurogenesis, indicated by reduced doublecortin+ immunoreactivity (DCX+IR), is paralleled by an increase in hippocampal pro...

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Bibliographic Details
Main Authors: Victoria Macht, Ryan Vetreno, Natalie Elchert, Fulton Crews
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Neuroinflammation
Subjects:
Proinflammatory
HMGB1
Doublecortin
Cyclooxygenase
Neuroprogenitor
Cell death
Online Access:https://doi.org/10.1186/s12974-021-02243-7

Internet

https://doi.org/10.1186/s12974-021-02243-7

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