Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure
Abstract Background Binge ethanol exposure during adolescence reduces hippocampal neurogenesis, a reduction which persists throughout adulthood despite abstinence. This loss of neurogenesis, indicated by reduced doublecortin+ immunoreactivity (DCX+IR), is paralleled by an increase in hippocampal pro...
Main Authors: | Victoria Macht, Ryan Vetreno, Natalie Elchert, Fulton Crews |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02243-7 |
Similar Items
-
Persistent Adult Neuroimmune Activation and Loss of Hippocampal Neurogenesis Following Adolescent Ethanol Exposure: Blockade by Exercise and the Anti-inflammatory Drug Indomethacin
by: Ryan P. Vetreno, et al.
Published: (2018-03-01) -
Inflammasome-IL-1β signaling mediates ethanol inhibition of hippocampal neurogenesis
by: Fulton eCrews
Published: (2012-05-01) -
Epigenetic regulation of microglia and neurons by proinflammatory signaling following adolescent intermittent ethanol (AIE) exposure and in human AUD
by: Fulton T. Crews, et al.
Published: (2024-03-01) -
Effect of Acute and Fractionated Irradiation on Hippocampal Neurogenesis
by: Jin Kyu Kim, et al.
Published: (2012-08-01) -
Adolescent Alcohol Exposure Produces Protracted Cognitive-Behavioral Impairments in Adult Male and Female Rats
by: Victoria Macht, et al.
Published: (2020-10-01)