Pattern recognition of topologically associating domains using deep learning

Abstract Background Recent increasing evidence indicates that three-dimensional chromosome structure plays an important role in genomic function. Topologically associating domains (TADs) are self-interacting regions that have been shown to be a chromosomal structural unit. During evolution, these ar...

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Bibliographic Details
Main Authors: Jhen Yuan Yang, Jia-Ming Chang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05075-1