Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors

The current work was conducted to synthesize several novel anti-inflammatory quinazolines having sulfamerazine moieties as new 3CLpro, cPLA2, and sPLA2 inhibitors. The thioureido derivative <b>3</b> was formed when compound <b>2</b> was treated with sulfamerazine. Also, compo...

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Bibliographic Details
Main Authors: Mohammed Abdalla Hussein, Rita M. Borik, Mohamed S. Nafie, Heba M. Abo-Salem, Sylvia A. Boshra, Zahraa N. Mohamed
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/16/6052