Mechanoregulation of MSC spheroid immunomodulation

Mesenchymal stromal cells (MSCs) are widely used in cell-based therapies and tissue regeneration for their potent secretome, which promotes host cell recruitment and modulates inflammation. Compared to monodisperse cells, MSC spheroids exhibit improved viability and increased secretion of immunomodu...

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Bibliographic Details
Main Authors: Victoria L. Thai, Sabrina Mierswa, Katherine H. Griffin, Joel D. Boerckel, J. Kent Leach
Format: Article
Language:English
Published: AIP Publishing LLC 2024-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0184431