A nanopore interface for higher bandwidth DNA computing

Toe-hold-mediated strand displacement (DSD) is a widely used molecular tool in applications such as DNA computing and nucleic acid diagnostics. Here the authors characterize dozens of orthogonal barcode sequences that can be used for monitoring the output kinetics of multiplexed DSD reactions in rea...

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Bibliographic Details
Main Authors: Karen Zhang, Yuan-Jyue Chen, Delaney Wilde, Kathryn Doroschak, Karin Strauss, Luis Ceze, Georg Seelig, Jeff Nivala
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32526-3