Singlet oxygen -derived nerve growth factor exacerbates airway hyperresponsiveness in a mouse model of asthma with mixed inflammation

Singlet oxygen -derived nerve growth factor exacerbates airway hyperresponsiveness in a mouse model of asthma with mixed inflammation

Background: Refractory asthma, which is caused by several factors including neutrophil infiltration is a serious complication of bronchial asthma. We previously reported that nerve growth factor (NGF) is involved in AHR. NGF-derived induction of hyperalgesia is dependent on neutrophils; however, thi...

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Bibliographic Details
Main Authors: Hirohisa Ogawa, Masahiko Azuma, Aya Umeno, Mayuko Shimizu, Kazutoshi Murotomi, Yasukazu Yoshida, Yasuhiko Nishioka, Koichi Tsuneyama
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Allergology International
Subjects:
Airway hyperresponsiveness
Nerve growth factor
Refractory asthma
Singlet oxygen
10- and 12-(Z,E)-hydroxyoctadecadienoic acids
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893022000132

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http://www.sciencedirect.com/science/article/pii/S1323893022000132

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