Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion

Summary: Epithelial-to-mesenchymal transition (EMT) is integral to cancer progression, with considerable evidence that EMT has multiple intermediary stages. Understanding the mechanisms of this stepwise activation is of great interest. We recreated a genetically defined model in which primary cells...

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Bibliographic Details
Main Authors: Laura S. Bisogno, Matthew B. Friedersdorf, Jack D. Keene
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900421830066X