Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

N-acyl taurines (NATs) are bioactive lipids with emerging roles in glucose homeostasis and lipid metabolism. The acyl chains of hepatic and biliary NATs are enriched in polyunsaturated fatty acids (PUFAs). Dietary supplementation with a class of PUFAs, the omega-3 fatty acids, increases their cognat...

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Bibliographic Details
Main Authors: Samuel A.J. Trammell, Luke F. Gamon, Kamil Gotfryd, Katja Thorøe Michler, Bandar D. Alrehaili, Iben Rix, Filip K. Knop, Pontus Gourdon, Yoon-Kwang Lee, Michael J. Davies, Matthew P. Gillum, Trisha J. Grevengoed
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Lipid Research
Subjects:
bile acids and salts/biosynthesis
bile acids and salts/metabolism
liver
omega-3 fatty acids
peroxisomes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000342

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http://www.sciencedirect.com/science/article/pii/S0022227523000342

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