Sensory Neurons, PIEZO Channels and PAC1 Receptors Regulate the Mechanosensitive Release of Soluble Ectonucleotidases in the Murine Urinary Bladder Lamina Propria

Sensory Neurons, PIEZO Channels and PAC1 Receptors Regulate the Mechanosensitive Release of Soluble Ectonucleotidases in the Murine Urinary Bladder Lamina Propria

The urinary bladder requires adequate concentrations of extracellular adenosine 5′-triphosphate (ATP) and other purines at receptor sites to function properly. Sequential dephosphorylation of ATP to ADP, AMP and adenosine (ADO) by membrane-bound and soluble ectonucleotidases (s-ENTDs) is essential f...

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Bibliographic Details
Main Authors: Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Mahsa Borhani Peikani, Violeta N. Mutafova-Yambolieva
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
ATP
urothelium
ectonucleotidases
PIEZO
PAC1 receptor
sensory neuropeptides
Online Access:https://www.mdpi.com/1422-0067/24/8/7322

Internet

https://www.mdpi.com/1422-0067/24/8/7322

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