Mechanisms of pentazocine-induced ventilatory depression and antinociception in anesthetized rats

This study was performed to clarify mechanisms underlying pentazocine-induced ventilatory depression and antinociception. Spontaneous ventilation and hind leg withdrawal response against nociceptive thermal stimulation were simultaneously recorded in anesthetized rats. Pentazocine decreased minute v...

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Bibliographic Details
Main Authors: Satoko Kimura, Yoshiaki Ohi, Akira Haji
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316000384