Oxidized low density lipoprotein in the liver causes decreased permeability of liver lymphatic- but not liver sinusoidal-endothelial cells via VEGFR-3 regulation of VE-Cadherin
The lymphatic vasculature of the liver is vital for liver function as it maintains fluid and protein homeostasis and is important for immune cell transport to the lymph node. Chronic liver disease is associated with increased expression of inflammatory mediators including oxidized low-density lipopr...
Main Authors: | Alyssa R. Goldberg, Megan Ferguson, Sarit Pal, Rachel Cohen, David J. Orlicky, Rebecca L. McCullough, Joseph M. Rutkowski, Matthew A. Burchill, Beth A. Jirón Tamburini |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-10-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.1021038/full |
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