A Methylazanediyl Bisacetamide Derivative Sensitizes Staphylococcus aureus Persisters to a Combination of Gentamicin And Daptomycin

A Methylazanediyl Bisacetamide Derivative Sensitizes Staphylococcus aureus Persisters to a Combination of Gentamicin And Daptomycin

Abstract Infections caused by Staphylococcus aureus, notably methicillin‐resistant S. aureus (MRSA), pose treatment challenges due to its ability to tolerate antibiotics and develop antibiotic resistance. The former, a mechanism independent of genetic changes, allows bacteria to withstand antibiotic...

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Bibliographic Details
Main Authors: Hee Young Heo, Guijin Zou, Seongeun Baek, Jae‐Seok Kim, Eleftherios Mylonakis, Frederick M. Ausubel, Huajian Gao, Wooseong Kim
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
antibiotic resistance
antibiotic tolerance
Caenorhabditis elegans
membrane‐active antimicrobials
methylazanediyl bisacetamide
MRSA
Online Access:https://doi.org/10.1002/advs.202306112

Internet

https://doi.org/10.1002/advs.202306112

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