Intestinal Pgc1α ablation protects from liver steatosis and fibrosis

Intestinal Pgc1α ablation protects from liver steatosis and fibrosis

Background & Aims: The gut–liver axis modulates the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), a spectrum of conditions characterised by hepatic steatosis and a progressive increase of inflammation and fibrosis, culminating in metabolic dysfunction-assoc...

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Bibliographic Details
Main Authors: Elena Piccinin, Maria Arconzo, Maria Laura Matrella, Marica Cariello, Arnaud Polizzi, Yannick Lippi, Justine Bertrand-Michel, Hervé Guillou, Nicolas Loiseau, Gaetano Villani, Antonio Moschetta
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:JHEP Reports
Subjects:
Metabolic dysfunction-associated steatotic liver disease
Metabolic dysfunction-associated steatohepatitis
Gut–liver axis
Cholesterol
Peroxisome proliferator-activated receptor-gamma coactivator 1α
NAFLD
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923001842

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http://www.sciencedirect.com/science/article/pii/S2589555923001842

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