Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice

Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice

Abstract Background Apical membrane antigen 1 (AMA1) and microneme-associated antigen (MIC) of Plasmodium parasites are important factors involved in host cell invasion. Methods In this study, influenza VLP vaccines containing both codon-optimized AMA1 and MIC were generated and the vaccine efficacy...

Full description

Bibliographic Details
Main Authors: Min-Ju Kim, Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Dong-Hun Lee, Su-Hwa Lee, Eun-Kyung Moon, Fu-Shi Quan
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Immunology
Subjects:
Plasmodium berghei
Apical membrane antigen 1
Microneme
Virus-like particles
Vaccine
Online Access:https://doi.org/10.1186/s12865-022-00494-4

Internet

https://doi.org/10.1186/s12865-022-00494-4

Similar Items