Revealing the Toxicity-Enhancing Essence of Glycyrrhiza on Genkwa Flos Based on Ultra-high-performance Liquid Chromatography Coupled With Quadrupole-Orbitrap High-Resolution Mass Spectrometry and Self-Assembled Supramolecular Technology

Revealing the Toxicity-Enhancing Essence of Glycyrrhiza on Genkwa Flos Based on Ultra-high-performance Liquid Chromatography Coupled With Quadrupole-Orbitrap High-Resolution Mass Spectrometry and Self-Assembled Supramolecular Technology

Researchers often focus on the mechanisms of synergistic agents, a few explore drug combinations that enhance toxicity, while few have studied the internal mechanism of compatibility enhancement in chemical level. Herein, we present a comprehensive analysis based on ultra-high-performance liquid chr...

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Bibliographic Details
Main Authors: Yuqin Yang, Feifei Li, Mengmeng Yan, Shan Chen, Desheng Cai, Xiaojing Liu, Nana Han, Zhihua Yuan, Jihui Lu, Yaozhi Zhang, Qiang Ma, Penglong Wang, Haimin Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Chemistry
Subjects:
genkwa flos
glycyrrhizic acid
ultra-high-performance liquid chromatography coupled with quadrupole-orbitrap high-resolution mass spectrometry
self-assembled supramolecular technology
toxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.740952/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.740952/full

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