Neutrophil cytosolic factor 2 (NCF2) gene polymorphism is associated with juvenile‐onset systemic lupus erythematosus, but probably not with other autoimmune rheumatic diseases in children

Neutrophil cytosolic factor 2 (NCF2) gene polymorphism is associated with juvenile‐onset systemic lupus erythematosus, but probably not with other autoimmune rheumatic diseases in children

Abstract Background Genetic variations of neutrophil cytosolic factor 2 (NCF2), a subunit of NADPH oxidase, are usually associated with chronic granulomatous disease, and their relationship with autoimmune disorders through the defective NADPH oxidase function during phagocytosis is suggested. Our s...

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Bibliographic Details
Main Authors: Ivan Y. Bakutenko, Irena D. Haurylchyk, Natalia V. Nikitchenko, Elena V. Sechko, Inna A. Kozyro, Alexei M. Tchitchko, Galina M. Batyan, Alexander V. Sukalo, Nadezhda I. Ryabokon
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
genetic risk factor
juvenile idiopathic arthritis
juvenile‐onset systemic lupus erythematosus
Kawasaki disease
NCF2 gene
Online Access:https://doi.org/10.1002/mgg3.1859

Internet

https://doi.org/10.1002/mgg3.1859

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