Reversal of the diabetic bone signature with anabolic therapies in mice

Abstract The mechanisms underlying the bone disease induced by diabetes are complex and not fully understood; and antiresorptive agents, the current standard of care, do not restore the weakened bone architecture. Herein, we reveal the diabetic bone signature in mice at the tissue, cell, and transcr...

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Bibliographic Details
Main Authors: Silvia Marino, Nisreen Akel, Shenyang Li, Meloney Cregor, Meghan Jones, Betiana Perez, Gaston Troncoso, Jomeeka Meeks, Scott Stewart, Amy Y. Sato, Intawat Nookaew, Teresita Bellido
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-023-00261-0