Amyotrophic lateral sclerosis: Correlations between fluid biomarkers of NfL, TDP-43, and tau, and clinical characteristics.

Amyotrophic lateral sclerosis: Correlations between fluid biomarkers of NfL, TDP-43, and tau, and clinical characteristics.

<h4>Objectives</h4>We previously reported the diagnostic and prognostic performance of neurofilament light chain (NfL), TAR DNA-binding protein 43 (TDP-43), and total tau (t-tau) in cerebrospinal fluid (CSF) and plasma as amyotrophic lateral sclerosis (ALS) biomarkers. The present study...

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Bibliographic Details
Main Authors: Yuta Kojima, Takashi Kasai, Yu-Ichi Noto, Takuma Ohmichi, Harutsugu Tatebe, Takamasa Kitaoji, Yukiko Tsuji, Fukiko Kitani-Morii, Makiko Shinomoto, David Allsop, Satoshi Teramukai, Toshiki Mizuno, Takahiko Tokuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0260323

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https://doi.org/10.1371/journal.pone.0260323

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