All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

Hepatocellular carcinoma (HCC), the main pathological type of liver cancer, is related to risk factors such as viral hepatitis, alcohol intake, and non-alcoholic fatty liver disease (NAFLD). The constitutive activation of the PI3K/AKT signaling pathway is common in HCC and has essential involvement...

Full description

Bibliographic Details
Main Authors: Ling-Yu Tian, Daniel J. Smit, Nadezhda V. Popova, Stefan Horn, Lis Noelia Velasquez, Samuel Huber, Manfred Jücker
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
AKT signaling
AKT isoforms
oxygen metabolism
lactate metabolism
extracellular acidification
glycolysis
Online Access:https://www.mdpi.com/1422-0067/25/4/2168

Internet

https://www.mdpi.com/1422-0067/25/4/2168

Similar Items