Protein Disulfide Isomerase expression increases in resistance arteries during hypertension development. Effects on Nox 1 NADPH oxidase signaling

Protein Disulfide Isomerase expression increases in resistance arteries during hypertension development. Effects on Nox 1 NADPH oxidase signaling

NADPH oxidases derived reactive oxygen species (ROS) play an important role in vascular function and remodeling in hypertension through redox signaling processes. Previous studies demonstrated that protein disulfide isomerase (PDI) regulates Nox1 expression and ROS generation in cultured vascular sm...

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Bibliographic Details
Main Authors: Aline Cristiane Depoli Androwiki, Lívia de Lucca Camargo, Simone Sartoretto, Gisele Kruger Couto, Izabela Martina Ramos Ribeiro, Sidney Verissimo-Filho, Luciana Venturini Rossoni, Lucia Rossetti Lopes
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Chemistry
Subjects:
Aorta
Hypertension
NADPH Oxidase
Reactive Oxygen Species
protein disulfide isomerase
Nox 1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00024/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00024/full

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