The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression.

This study investigated the efficiency of Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR) repair systems in rejoining DNA double-strand breaks (DSB) induced in CCD-34Lu cells by different γ-ray doses. The kinetics of DNA repair was assessed by analyzing the fluorescence decrease...

Full description

Bibliographic Details
Main Authors: Leonardo Bee, Sonia Fabris, Roberto Cherubini, Maddalena Mognato, Lucia Celotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3708908?pdf=render