Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3β/β-catenin signaling pathway.

Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3β/β-catenin signaling pathway.

Malignant gliomas represent one of the most aggressive types of cancers and their recurrence is closely linked to acquired therapeutic resistance. A combination of chemotherapy is considered a promising therapeutic model in overcoming therapeutic resistance and enhancing treatment efficacy. Herein,...

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Bibliographic Details
Main Authors: Cuixian Li, Chun Zhou, Shaogui Wang, Ying Feng, Wei Lin, Sisi Lin, Ying Wang, Heqing Huang, Peiqing Liu, Yong-Gao Mu, Xiaoyan Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3203172?pdf=render

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http://europepmc.org/articles/PMC3203172?pdf=render

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