Universal CARs, universal T cells, and universal CAR T cells
Abstract Currently, the two approved T cell products with chimeric antigen receptors (CAR) are from autologous T cells. These CAR T cells approved for clinical use must be generated on a custom-made basis. This case-by-case autologous T cell production platform remains a significant limiting factor...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
|
Series: | Journal of Hematology & Oncology |
Online Access: | http://link.springer.com/article/10.1186/s13045-018-0677-2 |