Soluble Klotho, a Potential Biomarker of Chronic Kidney Disease–Mineral Bone Disorders Involved in Healthy Ageing: Lights and Shadows

Soluble Klotho, a Potential Biomarker of Chronic Kidney Disease–Mineral Bone Disorders Involved in Healthy Ageing: Lights and Shadows

Shortly after the discovery of Klotho, interest grew in its potential role in chronic kidney disease (CKD). There are three isoforms of the Klotho protein: αKlotho, βKlotho and γKlotho. This review will focus on αKlotho due to its relevance as a biomarker in CKD. αKlotho is synthesized mainly in the...

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Bibliographic Details
Main Authors: Julia Martín-Vírgala, Beatriz Martín-Carro, Sara Fernández-Villabrille, María Piedad Ruiz-Torres, Carlos Gómez-Alonso, Minerva Rodríguez-García, José Luis Fernández-Martín, Cristina Alonso-Montes, Sara Panizo, Jorge B. Cannata-Andía, Manuel Naves-Díaz, Natalia Carrillo-López
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
serum sKlotho
urinary sKlotho
CKD
CKD-MBD
biomarker
healthy ageing
Online Access:https://www.mdpi.com/1422-0067/25/3/1843

Internet

https://www.mdpi.com/1422-0067/25/3/1843

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