Modulation of protein-DNA binding reveals mechanisms of spatiotemporal gene control in early Drosophila embryos

It is well known that enhancers regulate the spatiotemporal expression of their target genes by recruiting transcription factors (TFs) to the cognate binding sites in the region. However, the role of multiple binding sites for the same TFs and their specific spatial arrangement in determining the ov...

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Bibliographic Details
Main Authors: Sahla Syed, Yifei Duan, Bomyi Lim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85997