Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats

Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats

Loureirin B (LB) is the marker compound of dragon blood (DB), which exhibits great potentials in protecting astronauts’ health against radiation and simulated microgravity (SM). Pharmacokinetics of LB is reported to be significantly altered by SM. Here, we investigated key metabolic features of LB i...

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Prif Awduron: Bo Chen, Jingjing Guo, Shibo Wang, Liting Kang, Yulin Deng, Yujuan Li
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Frontiers Media S.A. 2018-10-01
Cyfres:Frontiers in Pharmacology
Pynciau:
simulated microgravity
dragon blood
loureirin B
liver microsome
hepatic cytochrome P450
drug metabolism
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fphar.2018.01130/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01130/full

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