Biophysical Characterization of Viral and Lipid-Based Vectors for Vaccines and Therapeutics with Light Scattering and Calorimetric Techniques

Novel vaccine platforms for delivery of nucleic acids based on viral and non-viral vectors, such as recombinant adeno associated viruses (rAAV) and lipid-based nanoparticles (LNPs), hold great promise. However, they pose significant manufacturing and analytical challenges due to their intrinsic stru...

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Bibliographic Details
Main Authors: Natalia Markova, Stefan Cairns, Hanna Jankevics-Jones, Michael Kaszuba, Fanny Caputo, Jérémie Parot
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/1/49