Osteogenic Effect of Pregabalin in Human Primary Mesenchymal Stem Cells, Osteoblasts, and Osteosarcoma Cells

Seventy million patients worldwide are suffering from epilepsy. The long-term use of antiepileptic drugs causes the alteration of the bone tissue and its metabolism, thus increasing the risk of fractures. Clinical and pre-clinical studies have highlighted conflicting data on the influence of the rel...

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Bibliographic Details
Main Authors: Nele Wagener, Pietro Di Fazio, Kai Oliver Böker, Georg Matziolis
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/4/496