Mitochondrial DNA variation in Parkinson’s disease: Analysis of “out-of-place” population variants as a risk factor

Mitochondrial DNA variation in Parkinson’s disease: Analysis of “out-of-place” population variants as a risk factor

Mitochondrial DNA (mtDNA), a potential source of mitochondrial dysfunction, has been implicated in Parkinson’s disease (PD). However, many previous studies investigating associations between mtDNA population variation and PD reported inconsistent or contradictory findings. Here, we investigated an a...

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Bibliographic Details
Main Authors: Amica C. Müller-Nedebock, Abigail L. Pfaff, Ilse S. Pienaar, Sulev Kõks, Francois H. van der Westhuizen, Joanna L. Elson, Soraya Bardien
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinsion’s disease
African ancestry
mitochondrial DNA
mtDNA
PPMI cohort
out-of-place variation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.921412/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.921412/full

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