Glycan processing in the Golgi as optimal information coding that constrains cisternal number and enzyme specificity

Many proteins that undergo sequential enzymatic modification in the Golgi cisternae are displayed at the plasma membrane as cell identity markers. The modified proteins, called glycans, represent a molecular code. The fidelity of this glycan code is measured by how accurately the glycan synthesis ma...

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Bibliographic Details
Main Authors: Alkesh Yadav, Quentin Vagne, Pierre Sens, Garud Iyengar, Madan Rao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/76757