A structure-based extracellular matrix expansion mechanism of fibrous tissue growth

Embryonic growth occurs predominately by an increase in cell number; little is known about growth mechanisms later in development when fibrous tissues account for the bulk of adult vertebrate mass. We present a model for fibrous tissue growth based on 3D-electron microscopy of mouse tendon. We show...

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Bibliographic Details
Main Authors: Nicholas S Kalson, Yinhui Lu, Susan H Taylor, Tobias Starborg, David F Holmes, Karl E Kadler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05958