Anti‐inflammatory effects of reticuline on the JAK2/STAT3/SOCS3 and p38 MAPK/NF‐κB signaling pathway in a mouse model of obesity‐associated asthma

Anti‐inflammatory effects of reticuline on the JAK2/STAT3/SOCS3 and p38 MAPK/NF‐κB signaling pathway in a mouse model of obesity‐associated asthma

Abstract Background Asthma associated with obesity is a chronic disease characterized by earlier airway remodeling, severe wheezing, and increased insensitivity to hormone therapy. Reticuline, a bioactive compound of Magnoliae Flos, exerts anti‐inflammatory activity and can inhibit neutrophil recrui...

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Bibliographic Details
Main Authors: Xiaojiang Lyu, Jiaojiao Liu, Zengrong Liu, Ying Wu, Ping Zhu, Chonghai Liu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:The Clinical Respiratory Journal
Subjects:
asthma
inflammation
JAK/STAT
neutrophil
obesity
SOCS3
Online Access:https://doi.org/10.1111/crj.13729

Internet

https://doi.org/10.1111/crj.13729

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