Downregulation of Notch Signaling‐Stimulated Genes in Neurovascular Unit Alterations Induced by Chronic Cerebral Hypoperfusion

Downregulation of Notch Signaling‐Stimulated Genes in Neurovascular Unit Alterations Induced by Chronic Cerebral Hypoperfusion

ABSTRACT Background Chronic cerebral hypoperfusion (CCH) is a key contributor to vascular cognitive impairment (VCI) and is typically associated with blood–brain barrier (BBB) damage. This study investigates the pathological mechanisms underlying CCH‐induced neurovascular unit (NVU) alterations. Met...

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Bibliographic Details
Main Authors: Dewen Ru, Zengyu Zhang, Meng Liu, Xuhui Fan, Yuqi Wang, Yufeng Yan, Ersong Wang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Immunity, Inflammation and Disease
Subjects:
brain microvessel
chronic cerebral hypoperfusion
microglial
neuroinflammation
Notch signaling pathway
Online Access:https://doi.org/10.1002/iid3.70082

Internet

https://doi.org/10.1002/iid3.70082

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