Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders

Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders

Abstract Background Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating autoimmune diseases in the central nervous system (CNS) that are characterized by a high relapse rate and the presence of anti-aquaporin 4 antibodies (AQP4-IgG) in the serum. Azathioprine (AZA) is a first-line immu...

詳細記述

書誌詳細
主要な著者: Xindi Li, Shenghui Mei, Xiaoqing Gong, Heng Zhou, Li Yang, Anna Zhou, Yonghong Liu, Xingang Li, Zhigang Zhao, Xinghu Zhang
フォーマット: 論文
言語:English
出版事項: BMC 2017-07-01
シリーズ:BMC Neurology
主題:
Neuromyelitis optica spectrum disorders (NMOSD)
Azathioprine (AZA)
Thiopurine S-methyltransferase (TPMT)
6-thioguanine nucleotides (6-TGNs)
6-methylmercaptopurine nucleotides (6-MMPNs)
オンライン･アクセス:http://link.springer.com/article/10.1186/s12883-017-0903-5

インターネット

http://link.springer.com/article/10.1186/s12883-017-0903-5

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