Biomimetic liposomal nanozymes improve breast cancer chemotherapy with enhanced penetration and alleviated hypoxia

Abstract Background Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of-care treatment of breast cancer. However, Dox therapy faces challenges such as hypoxia, acidosis, H2O2-rich conditions and condensed extracellular matrix in TME as well as low targeted ability. Meth...

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Bibliographic Details
Main Authors: Juanjuan Li, Chunai Gong, Xinlu Chen, Huanhuan Guo, Zongguang Tai, Nan Ding, Shen Gao, Yuan Gao
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-023-01874-7