Quantification of the TGF- β/SMAD fibrosis pathway in bladder wall samples from children with congenital lower urinary tract anomalies

Replacement of detrusor smooth muscle (SM) with connective tissue (CT) in the bladder wall has functional consequences to lower urinary tract function, namely changes to the filling compliance and its contractile performance. In children with congenital anomalies such tissue remodelling may underlie...

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Bibliographic Details
Main Authors: B. Xie, N. Johal, M. Millar, C. Thrasivoulou, A.J. Kanai, A. Ahmed, C.H. Fry
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Continence
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772973723000012