Laminin-α4 Is Upregulated in Both Human and Murine Models of Obesity

Laminin-α4 Is Upregulated in Both Human and Murine Models of Obesity

Obesity affects nearly one billion globally and can lead to life-threatening sequelae. Consequently, there is an urgent need for novel therapeutics. We have previously shown that laminin, alpha 4 (Lama4) knockout in mice leads to resistance to adipose tissue accumulation; however, the relationship b...

Full description

Bibliographic Details
Main Authors: Anna Goddi, Alanis Carmona, Liesl Schroedl, Jeremy M. White, Matthew J. Piron, Avelino De Leon, Isabel Casimiro, Alexandria Hoffman, Maria A. Gonzalez Porras, Eric M. Brey, Matthew J. Brady, Ronald N. Cohen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
laminins
extracellular matrix
basement membrane
adipose tissue
obesity
metabolic disease
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.698621/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.698621/full

Similar Items