The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans.
Candida albicans, like other pleiomorphic fungal pathogens, is able to undergo a reversible transition between single yeast-like cells and multicellular filaments. This morphogenetic process has long been considered as a key fungal virulence factor. Here, we identify the evolutionarily conserved Set...
Principais autores: | , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2010-05-01
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coleção: | PLoS Pathogens |
Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20485517/pdf/?tool=EBI |