The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans.

The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans.

Candida albicans, like other pleiomorphic fungal pathogens, is able to undergo a reversible transition between single yeast-like cells and multicellular filaments. This morphogenetic process has long been considered as a key fungal virulence factor. Here, we identify the evolutionarily conserved Set...

Bibliografski detalji
Glavni autori:	Denes Hnisz, Olivia Majer, Ingrid E Frohner, Vukoslav Komnenovic, Karl Kuchler
Format:	Članak
Jezik:	English
Izdano:	Public Library of Science (PLoS) 2010-05-01
Serija:	PLoS Pathogens
Online pristup:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20485517/pdf/?tool=EBI

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