Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes

Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes

Abstract Background Studies in animal models of Alzheimer’s disease (AD) have provided valuable insights into the molecular and cellular processes underlying neuronal network dysfunction. Whether and how AD-related neurophysiological alterations translate between mice and humans remains however unce...

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Bibliographic Details
Main Authors: Fran C. van Heusden, Anne M. van Nifterick, Bryan C. Souza, Arthur S. C. França, Ilse M. Nauta, Cornelis J. Stam, Philip Scheltens, August B. Smit, Alida A. Gouw, Ronald E. van Kesteren
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
Translational network neuroscience
Autosomal dominant Alzheimer’s disease
Mouse models of Alzheimer’s disease
Local field potential (LFP) recordings
Functional brain imaging
Online Access:https://doi.org/10.1186/s13195-023-01287-6

Internet

https://doi.org/10.1186/s13195-023-01287-6

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