Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle

During the asymmetric divisions of Drosophila neuroblasts, the Par polarity complex cycles between the cytoplasm and an apical cortical domain that restricts differentiation factors to the basal cortex. We used rapid imaging of the full cell volume to uncover the dynamic steps that underlie transiti...

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Bibliographic Details
Main Authors: Chet Huan Oon, Kenneth E Prehoda
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/45815