Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction

Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction

Background The pathobiology of heart failure with preserved ejection fraction (HFpEF) is still poorly understood, and effective therapies remain limited. Diabetes and mineralocorticoid excess are common and important pathophysiological factors that may synergistically promote HFpEF. The authors aime...

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Bibliographic Details
Main Authors: Bence Hegyi, Juliana Mira Hernandez, Christopher Y. Ko, Junyoung Hong, Erin Y. Shen, Emily R. Spencer, Daria Smoliarchuk, Manuel F. Navedo, Donald M. Bers, Julie Bossuyt
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
arrhythmia
diabetes
HFpEF
mineralocorticoid
SGLT2 inhibitor
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.027164

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.122.027164

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