Macrophages in Acute Myeloid Leukaemia: Significant Players in Therapy Resistance and Patient Outcomes

Macrophages in Acute Myeloid Leukaemia: Significant Players in Therapy Resistance and Patient Outcomes

Acute Myeloid Leukaemia (AML) is a commonly occurring severe haematological malignancy, with most patients exhibiting sub-optimal clinical outcomes. Therapy resistance significantly contributes towards failure of traditional and targeted treatments, disease relapse and mortality in AML patients. The...

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Bibliographic Details
Main Authors: Katerina E. Miari, Monica L. Guzman, Helen Wheadon, Mark T. S. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
patient outcomes
therapy resistance
BMME
M2-like macrophages
CD163+CD206+
acute myeloid leukaemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.692800/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.692800/full

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