A role for domain I of the hepatitis C virus NS5A protein in virus assembly.

The NS5A protein of hepatitis C virus (HCV) plays roles in both virus genome replication and assembly. NS5A comprises three domains, of these domain I is believed to be involved exclusively in genome replication. In contrast, domains II and III are required for the production of infectious virus par...

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Bibliographic Details
Main Authors: Chunhong Yin, Niluka Goonawardane, Hazel Stewart, Mark Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5792032?pdf=render