Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.

Nod-like receptors (NLRs) are important innate pattern recognition receptors and regulators of inflammation or play a role during development. We systematically analysed 41 non-synonymous single nucleotide polymorphisms (SNPs) in 21 NLR genes in a Czech discovery cohort of sporadic colorectal cancer...

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Main Authors: Stefanie Huhn, Miguel I da Silva Filho, Tharmila Sanmuganantham, Tica Pichulik, Calogerina Catalano, Barbara Pardini, Alessio Naccarati, Veronika Polakova-Vymetálkova, Katerina Jiraskova, Ludmila Vodickova, Pavel Vodicka, Markus W Löffler, Lioba Courth, Jan Wehkamp, Farhat V N Din, Maria Timofeeva, Susan M Farrington, Lina Jansen, Kari Hemminki, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister, Malcolm G Dunlop, Alexander N R Weber, Asta Försti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0199350