Iron regulatory proteins: players or pawns in ferroptosis and cancer?

Cells require iron for essential functions like energy production and signaling. However, iron can also engage in free radical formation and promote cell proliferation thereby contributing to both tumor initiation and growth. Thus, the amount of iron within the body and in individual cells is tightl...

Full description

Bibliographic Details
Main Authors: Cameron J. Cardona, McKale R. Montgomery
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1229710/full