Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice.

Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of gonadotropin-releasing hormone (GnRH) secretion in the hypothalamus. Recent studies have identified kisspeptin neurons of the hypothalamus as the t...

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Bibliographic Details
Main Authors: Arnon Gal, Po-Ching Lin, Joseph A Cacioppo, Patrick R Hannon, Megan M Mahoney, Andrew Wolfe, Rodrigo Fernandez-Valdivia, John P Lydon, Carol F Elias, CheMyong Ko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4956300?pdf=render