Determination of isotretinoin in human plasma: Application to pharmacokinetic study
A simple, rapid, sensitive and accurate HPLC–UV detection method was developed and validated for the determination of isotretinoin in human plasma. The method involves protein precipitation of plasma by acetonitrile using nifedipine as the internal standard (IS). Chromatographic separation was achie...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Pharmacy, Cairo University
2012-12-01
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| Series: | Bulletin of Faculty of Pharmacy Cairo University |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093112000348 |